Oxidation of diclofenac by birnessite: Identification of products and proposed transformation pathway


Xiaopeng Qin , Yue Zhao , Fei Liu , Min Wang

DOI:10.1016/j.jes.2020.05.017

Received March 23, 2020,Revised , Accepted May 18, 2020, Available online June 19, 2020

Volume 32,2020,Pages 169-178

Diclofenac (DCF), a widely used non-steroidal anti-inflammatory, reacted readily with birnessite under mild conditions, and the pseudo first order kinetic constants achieved 8.84 × 10−2 hr−1. Five products of DCF including an iminoquinone product (2,5-iminoquinone-diclofenac) and four dimer products were observed and identified by tandem mass spectrometry during the reaction. Meanwhile, 2,5-iminoquinone-diclofenac was identified to be the major product, accounting for 83.09% of the transformed DCF. According to the results of spectroscopic Mn(III) trapping experiments and X-ray Photoelectron Spectroscopy, Mn(IV) contained in birnessite solid was consumed and mainly converted into Mn(III) during reaction process, which proved that the removal of DCF by birnessite was through oxidation. Based on the identified products of DCF and the changes of Mn valence state in birnessite solid, a tentative transformation pathway of DCF was proposed.

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