TY - JOUR
ID - 10.1016/j.jes.2021.08.025
TI - Urinary analysis reveals high Alternaria mycotoxins exposure in the general population from Beijing, China
AU - Xiaoting Qiao
AU - Gang Li
AU - Jing Zhang
AU - Jing Du
AU - Yunjia Yang
AU - Jie Yin
AU - Hui Li
AU - Jie Xie
AU - You Jiang
AU - Xiang Fang
AU - Xinhua Dai
AU - Bing Shao
VL - 34
IS - 8
PB -
SP - 122
EP - 129
PY -
JF - Journal of Environmental Sciences
JA - J. Environ. Sci.
UR - http://www.jesc.ac.cn/jesc_en/ch/reader/view_abstract.aspx?file_no=S1001074221003296&flag=1
KW - Corresponding authors.;Biomonitoring;UPLC-MS/MS;Exposure assessment;Adults
AB - Alternaria mycotoxins are of concern due to its adverse health effect, they affect various cereal crops and grain-based food along with modified forms that contribute to overall exposure. This study aimed to determine the frequency and level of exposure to Alternaria mycotoxins (tenuazonic acid, TeA; alternariol, AOH; alternariol monomethyl ether, AME; tentoxin, TEN; and altenuene, ALT) in human urine from Beijing adults. A total of 2212 urine samples were collected and analyzed for five mycotoxins using LC–ESI–MS/MS. More than 98% of the samples had at least one Alternaria mycotoxin detected. Among the mycotoxins, AME had the highest detection rate (96.0%), followed by TeA (70.5%). The calculated average daily intake values of AME (12.5 ng/kg b.w.) was 5 times the TTC value (2.5 ng/kg b.w.) set by the EFSA, indicating the potential health risks associated with mycotoxins. Immediate attention and subsequent actions should be taken to identify the sources of mycotoxins and the corresponding exposure pathways to humans in the investigated regions.
ER -