Confirmation of combinational effects of calcium with other metals in a paperrecycling mill effluent on nematode lifespan with toxicityidentification evaluation method
Dayong Wang , Yang Wang , Lulu Shen
DOI:
Received August 09, 2009,Revised December 26, 2009, Accepted , Available online
Volume 22,2010,Pages 731-737
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We used toxicity identification evaluation (TIE) method to confirm the combinational e ects of identified toxic metals in a paper
recycling mill e uent in inducing the decreased lifespan in nematode Caenorhabditis elegans. Exposure to Ca + Al caused more
severely decreased lifespan than that exposed to Ca, or Al; and exposure to Ca + Fe induced more severely decreased lifespan than that
exposed to Ca, or Fe. Exposure to Ca+Al+Fe caused more severely decreased lifespan than that exposed to Ca, or Ca+Fe. Moreover,
the baseline toxicity on lifespan was doubled by doubling the concentration of combined metals (Ca+Al+Fe) in spiking test in original
e uent (oe), and lifespan defects in oe+Ca+Al+Fe exposed nematodes were more severe than that in Ca+Al+Fe exposed nematode.
Therefore, Ca+Al+Fe exposure may largely explain the formation of decreased lifespan induced by the examined industrial e uent.
Furthermore, the observed reduction of lifespan induced by the combination of high level of Ca with other metals may be at least
partially independent of the insulin-like pathway.
